Player Draft
| Name | State | School | Class | Pos. | Year | Round | Team |
| Malique Ziegler | IA | Des Moines East | 2014 | OF | 2016 | 22 | Giants |
| Calvin Ziegler | ON | TNXL Academy | 2021 | RHP | 2021 | 2 | New York Mets |
| Gage Ziehl | NY | Penfield | 2021 | RHP | 2024 | 4 | Yankees |
| Zane Zielinski | IL | Lake View | 2020 | SS | 2024 | 9 | Giants |
| Michael Zimmerman | FL | Gulf Coast | 2015 | LHP | 2015 | 11 | Rockies |
| Keegan Zinn | FL | Lake Minneola | 2023 | RHP | 2023 | 12 | Guardians |
| Jake Zitella | IL | St. Charles East | 2023 | 3B | 2023 | 16 | Mets |
| Steven Zobac | CA | Valley Christian | 2019 | RHP | 2022 | 4 | Royals |
| Nick Zona | VA | Hanover | 2018 | RHP | 2022 | 20 | Mariners |
| Donovan Zsak | NJ | St. Joseph's Metuchen | 2022 | LHP | 2024 | 8 | Guardians |
| Nick Zwack | MN | Monticello | 2017 | LHP | 2021 | 17th | NY Mets |
| Tony Zych | IL | St. Rita | 2008 | RHP | 2011 | 4 | Cubs |